Kodon

Kodon (Inggeris: Codon) sanga tinanda muse "Kode genetik" ima urutan ni nukleotida di mRNA na adong 3 kombinasi nukleotida marurutan^[1] gabe marsada sada asam amino tertentu.^[2] gabe jotjot dijou kodon triplet.^[3] Asam amino na disandihan misalna metionin di urutan nukleotida ATG (AUG di RNA).^[3] Bahat asam amino na disandihan lumobi sian sada jenis kodon.^[4]

Kodon on adong di molekul mRNA.^[5] Lapatanan ni mRNA gabe protein diulahon di ruas panyandi na diapit nikodon awal (AUG) dohot kodon akhir (UAA, UAG sanga UGA), ruas on dijou gen.^[6] Kodon di molekul mRNA boi gabe sandi asam-asam amino dohot pangurupion interpretasi kodon ni tRNA.^[5] Sude tRNA mamboan sada asam amino turpuk tu tolu urutan nukleotida sanga pe triplet, dijou ma i antikodon na adong di simpul antikodon tRNA.^[5] Antikodon tarikat songonna komplementer tu kodon ni mRNA, jadina asam amino na diboan ni tRNA hombar tu kodon na adong di mRNA.^[5].

Kodon awal dohot kodon akhir

Kodon awal ima kodon perjolo na dilapatani tingki mambahen translasi, sanga dijou muse kodon inisiasi (AUG na mambahen sandi metionin).^[7] Na asing sian kodon inisiasi, naeng mangulahon translasi dihaporluhon ima sekuen sanga situs na dijou Shine-Dalgarno na hasea tu panandaan ni ribosom na ditumpaki faktor inisiasi (tolu jenis protein).

Molo Kodon akhir ima sada sian tolu kodon na adong, ima UAG, UAA sanga UGA.^[8] Kodon akhir dijou muse gabe kodon terminal na so mabahen sandi asam amino.^[8] Kodon akhir membahen proses translasi gabe marujung dohot tumpak ni faktor pelepasan asa boi paluahon ribosom.^[8]

Pustaha

↑ Anthony JF Griffiths, Jeffrey H Miller, David T Suzuki, Richard C Lewontin, and William M Gelbart (2000) "An Introduction to Genetic Analysis, Edition 7" University of British Columbia, University of California, Harvard University, isbn: 0-7167-3520-2, halaman : Genes as determinants of the inherent properties of species, diterbitkan oleh W. H. Freeman, diakses 22 November 2020, [1]
↑ [2]
↑ ^3.0 ^3.1 Yuwono T. 2005. Biologi Molekuler. Jakarta: Erlangga.
↑ Dale JW & Park SF (2004) Molecular genetics of Bacteria. Chichester: John Willey & Sons Ltd.
↑ ^5.0 ^5.1 ^5.2 ^5.3 Campbell NA, Reece BJ, Mitchell LG (2002) Biologi. Jakarta: Erlangga
↑ Jusuf M. 2001. Genetika I: Struktur dan Ekspresi Gen. Jakarta: Sagung Seto
↑ Touriol C, Bornes S, Bonnal S, Audigier S, Prats H, Prats AC, Vagner S (2003) Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons. Biol. Cell 95 (3-4): 169–78
↑ ^8.0 ^8.1 ^8.2 Maloy S (2003) Microbial Genetics Course. San Diego University

[1] Anthony JF Griffiths, Jeffrey H Miller, David T Suzuki, Richard C Lewontin, and William M Gelbart (2000) "An Introduction to Genetic Analysis, Edition 7" University of British Columbia, University of California, Harvard University, isbn: 0-7167-3520-2, halaman : Genes as determinants of the inherent properties of species, diterbitkan oleh W. H. Freeman, diakses 22 November 2020, [1]

[2] [2]

[Yuwono_T.-3] 3.0 ^3.1 Yuwono T. 2005. Biologi Molekuler. Jakarta: Erlangga.

[Dale_JW_&_Park_SF.-4] Dale JW & Park SF (2004) Molecular genetics of Bacteria. Chichester: John Willey & Sons Ltd.

[Campbell_NA_''et_al.''-5] 5.0 ^5.1 ^5.2 ^5.3 Campbell NA, Reece BJ, Mitchell LG (2002) Biologi. Jakarta: Erlangga

[Jusuf_M.-6] Jusuf M. 2001. Genetika I: Struktur dan Ekspresi Gen. Jakarta: Sagung Seto

[Touriol_C,_''et_al''.-7] Touriol C, Bornes S, Bonnal S, Audigier S, Prats H, Prats AC, Vagner S (2003) Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons. Biol. Cell 95 (3-4): 169–78

[Maloy_S-8] 8.0 ^8.1 ^8.2 Maloy S (2003) Microbial Genetics Course. San Diego University

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]